The article highlights the story of a lymphoma patient who experienced a relapse after initial treatments including CD19 CAR-T therapy. Seeking alternative options, the patient participated in a novel CAR T-cell therapy trial at City of Hope. This innovative treatment (BAFFR CAR-T) involved reengineering the patient’s own T-cells to better target cancer cells. After undergoing the trial, the patient achieved a remarkable remission. The article emphasizes the hope that BAFFR CAR T-cell therapy offers for patients with difficult-to-treat lymphomas. It also discusses the ongoing research and advancements in immunotherapy. The patient’s journey showcases resilience and the potential for groundbreaking treatments in oncology. Overall, it illustrates the positive impact of clinical trials on patient outcomes.

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